Eleven South African golfers will tee off in Thursday's PGA Championship at Southern Hills Country Club in Tulsa.
2011 Masters champion Charl Schwartzel gained a late entry after defending champion Phil Mickelson withdrew from this week's major.
It's a joint record of major participation for South Africa, which also saw 11 golfers take part in last year's PGA Championship at Kiawah Island.
South Africa's top-ranked golfer, Louis Oosthuizen, finished runner-up to Mickelson to sit on 4-under alongside Brooks Koepka - two strokes behind Mickelson.
The last time a South African lifted the famed Wanamaker Trophy was in 1972, when Gary Player won by two strokes for his second PGA Championship title.
South African golfer Oliver Bekker, who has had a marvellous run on the Sunshine Tour and DP World Tour, will be making his PGA Championship debut this week.
Dean Burmester will be the first South African to tee off as he starts his opening round at 14:22 SA time, alongside American duo Kyle Mendoza and Chris Kirk.
Schwartzel tees off in round one with Spaniard Sergio Garcia and in-form Matthew Fitzpatrick of England at 21:09 SA time.
Meanwhile, major winners Tiger Woods, Jordan Spieth and Rory McIlroy were grouped together for the opening two rounds at 15:11 SA time.
World number one Scottie Scheffler of the United States goes off at 20:36 SA time alongside reigning US Open champion Jon Rahm of Spain and reigning Open champion Collin Morikawa of the United States.
Featured pairings for Round 1 of the PGA Championship:
14:22 - Dean Burmester, Kyle Mendoza, Chris Kirk
14:44 - Kevin Streelman, Shaun Norris, Carlos Ortiz
15:28 - Richard Bland, Matt Jones, Garrick Higgo
15:11 - Jordan Spieth, Rory McIlroy, Tiger Woods
15:33 - Kevin Na, Lucas Glover, Daniel van Tonder
16:04 - Brian Harman, Ryan Vermeer, Oliver Bekker
19:41 - Nicolai Hojgaard, Sean McCarty, Justin Harding
20:03 - Shane Lowry, Brooks Koepka, Adam Scott
20:09 - Jason Kokrak, Corey Conners, Christiaan Bezuidenhout
20:14 - Dustin Johnson, Patrick Cantlay, Justin Thomas
20:36 - Jon Rahm, Collin Morikawa, Scottie Scheffler
20:42 - Webb Simpson, Branden Grace, Henrik Stenson
20:47 - Daniel Berger, Louis Oosthuizen, Ian Poulter
21:09 - Sergio Garcia, Charl Schwartzel, Matt Fitzpatrick
21:20 - Harry Higgs, Joaquin Niemann, Erik van Rooyen